- SpongeBob SquarePants
- Squidward Tentacles
- Gary the Snail
- Patrick Star
- Eugene H. Krabs
- Dr. Gill Gilliam (name revealed)
- Realistic Fish Head
- Perch Perkins
- Old Man Walker
- Bikini Bottomites
Squidward walks outside to find his yard covered in Gary's slime-trail. He attempts to keep Gary away by building a splintery wooden fence around him, but to no avail. As he complains to SpongeBob about this, and Gary bites him. Squidward asks SpongeBob if Gary has had all of his shots, and he says that he has, until Patrick comes along and asks him if Gary has been vaccinated for "Mad Snail Disease", a disease that turns anyone bitten by the afflicted into a zombie, which SpongeBob says he has not. Suddenly, Gary runs off and starts to bite everybody in sight.
Bikini Bottom is sent into a state of mass hysteria and destruction, and soon, almost everybody has been bitten and turned into zombies. Those who have survived the disease are hiding out at the Krusty Krab. SpongeBob tries to get in, but they believe he is a zombie and will not let him in, until he slips through the doors. An old man suggests that they might all be zombies, and everyone starts panicking. Gary then comes in, much to the horror of the onlookers, and SpongeBob tries to bring him to his senses, but Gary bites him and he seemingly turns into a zombie too much to his sadness and horror. The survivors in the Krusty Krab decide to terminate Gary.
However, a doctor named Gill Gilliam enters the building to put an end to the commotion, explaining that the disease is just an urban legend and that the supposed symptoms were all in their imaginations, and that Gary was simply suffering from "Grouchy Snailitis" due to a "tiny" splinter in his foot from Squidward's fence, which he removes. SpongeBob is happy that Gary was never disease-ridden and asks if he still loves him with Gary meowing in response. The remaining people outside appear to hear this and even though they are not infected, Squidward still acts like a zombie due to the fact that he is now working at his job. The episode ends with Gary biting Mr. Krabs.
APM Music Identification
- Marching to Honolulu - Title card
- Comic Walk - "Snail trail."
- Tomfoolery - "This cheap splintery wood will keep even Gary out!"
- Dramatic Impact 3 - SpongeBob and Patrick realize Gary's gone
- Lambs in Clover - "Oh, look, honey. Isn't he the cutest?"
- The Tip Top Polka/Cliff Polka - "SpongeBob! Come on in, boy!"
- Wooden Bear - Gil Gilliam introduces himself
- Old Hilo March - Gary bites Mr. Krabs.
- Mad Snail Disease is a reference to Mad Cow Disease, aka bovine spongiform encephalopathy (BSE). Ironically, Mad Snail Disease is more similar to rabies than it is to Mad Cow Disease.
- The title card background of this episode is similar to those of "The Chaperone" and "Born Again Krabs," though it is red instead of light blue, there are flowers added, there are no bubbles, and there is no 4:3 aspect ratio-like thing in it.
- How could a huge pole fit inside Gary's foot? It may be because it is a cartoon.
- People will think they're zombies again in The Krusty Sponge.
- Once Bitten is based on the phrase, "Once Bitten, Twice Shy", which means if someone is hurt by someone or something before, they will be more cautious next time.
- One of the Bikini Bottomites says that the diesease is spreading through the air even though they are underwater.
- The second part of this episode where the fishes turn into "zombies" is a parody of the George Romero movie"Night Of The Living Dead".
- If you think very closely that the cause of everything in this episode is because Spongebob because he allows Gary to Squidward's house and also Squidward to also the cause too because he made the poles he could just used the shocking cage like he used in Breath of Fresh Squidward .
- It is never seen how Gary got the huge pole stuck.
- This episode may imply that Gary hates Mr. Krabs.
- Gary bitten all because I was grumpy because I had a splinter embedded, but for gary bite everyone should touch the splinter area causing more pain and descitarse to bite and only touched it in the shell.